Microarray Analysis of Human Dental Follicle Cells in Osteogenic Differentiation
نویسندگان
چکیده
منابع مشابه
Osteogenic Differentiation of Dental Follicle Stem Cells
BACKGROUND Stem cells are defined as clonogenic cells capable of self-renewal and multi-lineage differentiation. A population of these cells has been identified in human Dental Follicle (DF). Dental Follicle Stem Cells (DFSCs) were found in pediatric unerupted wisdom teeth and have been shown to differentiate, under particular conditions, into various cell types of the mesenchymal tissues. AI...
متن کاملThe dexamethasone induced osteogenic differentiation of dental follicle cells.
Mesenchymal stem cells are excellent for in vitro studies about biological processes during the differentiation of osteogenic progenitor cells into mineralizing cells such as osteoblasts. Human dental follicle cells (DFCs) are dental mesenchymal stem cells and they can be isolated from third molar teeth. Because DFCs are the genuine progenitor cells of periodontal tissue cells, they have been u...
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Background: Periodontal ligament stem cells (PDLSCs) are considered as a type of mesenchymal stem cell that is beneficial target for numerous clinical applications in periodontal tissue regeneration therapy. Materials and Methods: This study examined the effects of dexamethasone (Dex) on human PDLSCs in vitro. PDLSCs obtained from the roots of patient’s teeth were cultured with Dex (0....
متن کاملComparison of Odontogenic Differentiation of Human Dental Follicle Cells and Human Dental Papilla Cells
Classical tooth development theory suggests that dental papilla cells (DPCs) are the precursor cells of odontoblasts, which are responsible for dentin development. However, our previous studies have indicated that dental follicle cells (DFCs) can differentiate into odontoblasts. To further our understanding of tooth development, and the differences in dentinogenesis between DFCs and DPCs, the o...
متن کاملMicroarray analysis of osteogenesis gene of human dental follicle cells stimulated with dexamethasone in vitro
Purpose: To examine osteoblastic genes expression of freshly isolated human dental follicle cells during osteogenic differentiation in vitro using cDNA microarrays. Materials and Methods: The dental follicle cells isolated from dental follicle were cultured in DMEM media with 10 mol/L Dex for 4 weeks, the control without Dex. Total RNA was extracted from the cultured follicle cells with Trizol....
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ژورنال
عنوان ژورنال: Journal of Hard Tissue Biology
سال: 2009
ISSN: 1341-7649,1880-828X
DOI: 10.2485/jhtb.18.27